Tips on Preserving Temperature Sensitive Biological Specimen

It is mandatory that all biospecimens should be well stored and preserved because they take the time to develop. Biological specimens are mainly common in a medical laboratory and biological laboratories. All the biological specimens must be well preserved before the experiments using the most appropriate techniques. Consult Cryosend for proper storage and transportation of your specimen. The specimens should also be stored in pleasant temperatures that will not alter the biological composition of the specimens. Today there are numerous techniques of storing specimens in the laboratory and most of them are very effective even if it all depends on the type of the specimen.

Preserving specimen

Fixation process

Biologically, fixation is the first step in preserving biological spPreserving specimenecimens. It includes the cessation/killing of the normal life functions of the specimen. This step is critical in the process of preserving biological specimens. The process of fixation also stabilizes the biological structure of the specimen.

The biological expert should ensure that the specimen’s tissues are not damaged at all because this process also requires the expert to maintain a small size of the tissue. The process is made possible by keeping the specimen moist before the fixation procedure. This is done by submerging the specimen in a wetting agent some minutes before the fixation procedure.

Dehydrating the specimen

Dehydration can be well explained as the chemical/biological process of removing water from a specimen. The best dehydration agents that are available in the market today are acetone and ethanol. This process is very crucial even if there are possible side effects of the specimen shrinking in size and losing the soluble elements in its structure.

Infiltration process

It’s a crucial process that involves, placing the specimen in a plastic resin. In this step, the specimen is not damaged by resin. The aim of this procedure is to ensure that resin penetrates into the specimen.


It’s the final step that requires you to position the specimen in a liquid plastic. The procedure involves the use of three molds namely; small capsules (e.g. gelatin), flat-embedded capsules and flat dishes. The process is quite paramount because it determines the orientation f sectioning gelatin and BEEM in times when the specimen does not have polarity.

The flat dish molds are useful when the specimen is large or when the specimen is somehow impractical; the flat-embedded capsules are used when the specimen requires an orientation process to a particular position in the liquid plastic.